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Novel C‐acylated triazole derivatives of ravuconazole, an azole antifungal agent
Author(s) -
Kim Oak,
Zhang Yunhui,
Wichtowski John,
Huang Stella,
FungTomc Joan,
Bronson Joanne,
Ueda Yasutsugu
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450245
Subject(s) - chemistry , azole , antifungal , triazole , combinatorial chemistry , stereochemistry , organic chemistry , microbiology and biotechnology , biology
Novel C‐acylated triazoles were synthesized from ravuconazole via bicyclic triazole lactone. The synthesis and antifungal activity of these C‐acylated derivatives are described.