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Iodine catalyzed synthesis of α,α'‐bis(substituted benzylidene)‐1‐carbethoxy‐4‐piperidone
Author(s) -
Ameen Mohame D. A.,
Ahmed Essam, Kh.
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450244
Subject(s) - chemistry , acetonitrile , catalysis , iodine , combinatorial chemistry , medicinal chemistry , organic chemistry
A facile and efficient method for the preparation of α,α′‐bis(substituted benzylidene)‐1‐carbethoxy‐4‐piperidone is described using iodine as a catalyst in acetonitrile. The reaction proceeds rapidly at room temperature, giving high yields of products.