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Synthesis of 2,4‐difuryl‐4 H ‐3,1‐benzothiazines via a furan ring migration reaction
Author(s) -
Abaev Vladimir T.,
Tsiunchik Fatima A.,
Butin Alexander V.,
Gutnov Andrey V.
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450227
Subject(s) - chemistry , furan , intramolecular force , ring (chemistry) , electrophile , catalysis , medicinal chemistry , bicyclic molecule , stereochemistry , combinatorial chemistry , organic chemistry
A new simple synthetic approach to 2,4‐difuryl‐4 H ‐3,1‐benzothiazines from 2‐isothiocyanoaryldifuryl‐methanes in the presence of acidic catalyst is described. This rearrangement is a new example of furan ring migration reaction resulting from intramolecular attack with electrophilic carbon.