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Application of the acetate of baylis‐hillman adducts in the synthesis of 3‐carbomethoxy‐2 H ‐thiochromenes
Author(s) -
Cha Myeong Jong,
Song Young Seok,
Han EunGu,
Lee KeeJung
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450129
Subject(s) - chemistry , substituent , adduct , halogen , dimethyl sulfoxide , sodium sulfide , sulfide , sulfoxide , tandem , aqueous solution , organic chemistry , nitro , medicinal chemistry , alkyl , materials science , composite material
A new route to 2 H ‐thiochromenes using the tandem S N 2′ and S N Ar reaction of several Baylis‐Hillman acetates having an ortho ‐substituent, such as a halogen or nitro group, with sodium sulfide in aqueous dimethyl sulfoxide has been described.