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Regioselective three‐component synthesis of novel indeno[1,2‐ b ]‐pyrazolo[4,3‐ e ]pyridines‐fused derivatives of 4‐azafluorenone alkaloid
Author(s) -
Quiroga Jairo,
Cobo Débora,
Insuasty Braulio,
Abonía Rodrigo,
Cruz Silvia,
Nogueras Manuel,
Cobo Justo
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450116
Subject(s) - chemistry , benzaldehyde , regioselectivity , pyridine , component (thermodynamics) , stereochemistry , alkaloid , organic chemistry , catalysis , physics , thermodynamics
New fused indeno[1,2‐ b ]pyridine derivatives have been prepared in a multicomponent reaction from benzaldehydes, indanedione and the appropriate aminoheteroaryl compound. The simple methodology permitted the syntheses of a series of indeno[1,2‐ b ]pyrazolo[4,3‐ e ]pyridines 4 from 5‐aminopyrazol 1 and modulated by the corresponding benzaldehyde 2 .

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