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The synthesis of a linear tröger's base derived from naphthalene: 7 H ‐15 H ‐6,14‐methanodinaphtho[2,3‐ b :2′,3′‐ f ][1,5]diazocine
Author(s) -
Pardo Carmen,
Pirat Céline,
Elguero José
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440611
Subject(s) - chemistry , naphthalene , yield (engineering) , base (topology) , stereochemistry , medicinal chemistry , organic chemistry , mathematical analysis , mathematics , materials science , metallurgy
The title compound 3 was prepared in four steps from commercial 3‐amino‐2‐naphthoic acid in an overall 75 % yield. Attempts to use the same approach in the case of 2‐aminonicotinic acid methyl ester failed. All the compounds were characterized by NMR.