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An unusual picoline derivative from the trifluoroacetolysis of thiostrepton
Author(s) -
Merritt Eleanor A.,
Bagley Mark C.
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440609
Subject(s) - thiostrepton , chemistry , picoline , methanol , aqueous solution , derivative (finance) , pyridine , sodium hydroxide , nuclear chemistry , medicinal chemistry , organic chemistry , biochemistry , rna , ribosome , financial economics , economics , gene
Trifluoroacetolysis of thiostrepton followed by treatment with methanol and aqueous sodium hydroxide led to the formation of N ‐(2‐picolinoyl)serine methyl ester, the first pyridine‐containing compound isolated from the chemical degradation of thiostrepton.