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An efficient and greener approach to the synthesis of 3,5‐dicyanopyridin‐2(1 H )‐one derivatives in aqueous media under microwave irradiation conditions
Author(s) -
Jia Runhong,
Tu Shujiang,
Zhang Yan,
Jiang Bo,
Zhang Junyong,
Yao Changsheng,
Shi Feng
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440533
Subject(s) - malononitrile , chemistry , microwave irradiation , aqueous medium , aldehyde , aqueous solution , microwave , sodium hydroxide , organic chemistry , nuclear chemistry , catalysis , physics , quantum mechanics
A facile and greener synthesis of a series of 3,5‐dicyanopyridin‐2(1 H )‐one derivatives was accomplished via the one‐pot reaction of aldehyde, malononitrile and sodium hydroxide in aqueous media under microwave irradiation. This method had several advantages such as shorter route and time, lower cost, reduced environmental impact.