z-logo
Premium
Reaction of 1‐acylthiosemicarbazides with ethenetetracarbonitrile
Author(s) -
Hassan Alaa A.,
Mourad AboulFetouh E.,
AbouZied Ashraf H.
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440532
Subject(s) - chemistry , hydrazide , oxadiazole , medicinal chemistry , stereochemistry , organic chemistry
1‐Acylthiosemicarbazides 9a‐d reacted with ethenetetracarbonitrile (TCNE, 2 ) in ethyl acetate with formation of N ′‐(4‐amino‐5,6‐dicyano‐2 H ‐1,3‐thiazin‐2‐ylidene) substituted hydrazide 10a‐d , N ′‐(5‐amino‐3,4‐dicyano‐2 H ‐pyrrol‐2‐ylidene)‐2‐substituted hydrazide 11a‐d and 2‐substituted imidazo[2,1‐ b ][1,3,4]‐oxadiazole‐5,6‐dicarbonitrile 12a‐d . Rationales for the conversions observed are presented.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom