Microwave assisted synthesis of thiazolo[3,2‐ b ][1,2,4]‐triazoles containing 1,8‐naphthyridine moiety | Zendy

Mogilaiah K. | Zendy; Prashanthi M. | Zendy; Kavitha S. | Zendy; Babu H. Sharath | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Microwave assisted synthesis of thiazolo[3,2‐ b ][1,2,4]‐triazoles containing 1,8‐naphthyridine moiety

Author(s) -

Mogilaiah K.,

Prashanthi M.,

Kavitha S.,

Babu H. Sharath

Publication year - 2007

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570440530

Subject(s) - chemistry , moiety , methanol , microwave irradiation , aryl , microwave , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry , catalysis , alkyl , physics , quantum mechanics

A simple and efficient protocol for the synthesis of 5‐aryl‐2‐(2‐substituted‐1,8‐naphthyridin‐3‐yl)‐thiazolo[3,2‐ b ][1,2,4]triazoles ( 4 ) is achieved by cyclocondensation of 3‐(2‐substituted‐1,8‐naphthyridin‐3‐yl)‐1,2,4‐triazoles ( 3 ) with α‐halogenoketones in anhyd. methanol under microwave irradiation. The products are obtained in good yields and in a state of high purity.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research