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Synthesis and crystal structure of novel schiff bases derived from 3‐(2‐ethoxyphenyl)‐4‐amino‐5‐mercapto‐4 H ‐1,2,4‐triazole
Author(s) -
Zhou Sannu,
Zhang Lixue,
Zhang Anjiang,
Sheng Jishun,
Zhang Haile
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440507
Subject(s) - chemistry , crystal structure , 1,2,4 triazole , triazole , medicinal chemistry , stereochemistry , organic chemistry
A series of novel 4‐(arylmethylidene)amino‐5‐(2‐ethoxyphenyl)‐3‐mercapto‐4 H ‐1,2,4‐triazoles ( 2a‐f ) were easily synthesized in high yields by means of the reactions of 3‐(2‐ethoxyphenyl)‐4‐amino‐5‐mercapto‐4 H ‐1,2,4‐triazole ( 1 ) with various aromatic aldehydes. The compound, 4‐(4‐methylbenzylidene)‐amino‐5‐(2‐ethoxyphenyl)‐3‐mercapto‐4 H ‐1,2,4‐triazole was investigated with X‐ray crystallography.