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An efficient synthesis of new class of pyrazolo[3,4‐ b ]pyridine‐6‐one derivatives by a novel cascade reaction
Author(s) -
Shi Feng,
Zhang Junyong,
Tu Shujiang,
Jia Runhong,
Zhang Yan,
Jiang Bo,
Jiang Hong
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440506
Subject(s) - chemistry , pyridine , cascade , amine gas treating , cascade reaction , combinatorial chemistry , reaction conditions , medicinal chemistry , organic chemistry , stereochemistry , catalysis , chromatography
A novel cascade reaction of 4‐arylidene‐2‐phenyl‐1,3‐oxazol‐5(4 H )‐one with 3‐methyl‐1‐phenyl‐1 H ‐pyrazol‐5‐amine was described and a number of new pyrazolo[3,4‐ b ]pyridine‐6‐one derivatives were synthesized. This new protocol has the advantages of shorter time, higher yields, and lower cost as well as easier operation.