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A new synthetic route to the synthesis of nordasycarpidone derivatives
Author(s) -
Akdag Resmiye,
Ergun Yavuz
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440418
Subject(s) - chemistry , derivative (finance) , nitrile , catalytic hydrogenation , combinatorial chemistry , total synthesis , catalysis , stereochemistry , organic chemistry , financial economics , economics
A new synthetic route for the synthesis of the nordasycarpidone derivative 11 which has hexahydro‐1,5‐methanoazocino[4,3‐ b ]indol skeleton, is described. Construction of the tetracyclic structure was achieved by catalytic reduction and cyclization reaction of the nitrile derivative. Also many new tetrahydrocarbazole derivatives ( 4, 5, 6, 7, 8, 9 ) and a dasycarpidol derivative ( 10 ) were synthesized.