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Synthesis of some pyrazolopyrimidines as purine analogues
Author(s) -
Ahmed Sayed A.,
Hussein Ahmed M.,
Hozayen Walaa G. M.,
ElGhandour Ahmed H. H.,
Abdelhamid Abdou O.
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440408
Subject(s) - chemistry , acrylonitrile , purine , diketone , combinatorial chemistry , organic chemistry , stereochemistry , copolymer , enzyme , polymer
Pyrazolo[1,5‐ a ]pyrimidines were synthesized from the appropriate 3‐aminopyrazoles with the appropriate sodium (3‐oxocycloalkylidene)methenolate, β‐diketone, β‐keto esters or 1,2‐disubstituted acrylonitrile. Elemental analyses, spectral data, alternative synthesis route and X‐ray elucidated structures of the newly synthesized compounds.