Premium
Cycloaddition reactions with 2,3‐benzodiazepine derivatives
Author(s) -
Kertész Máriusz,
Pallagi István,
Sólyom Sándor
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440224
Subject(s) - chemistry , diazomethane , cycloaddition , nitrile , benzodiazepine , reactivity (psychology) , ring (chemistry) , 1,3 dipolar cycloaddition , medicinal chemistry , propargyl , double bond , organic chemistry , catalysis , medicine , biochemistry , receptor , alternative medicine , pathology
We report here on some 3+2 dipolar cycloaddition reactions of propargyl, allyl and cyano substituted 2,3‐benzodiazepines with in situ generated nitrile oxides and diazomethane. The reactivity of carbon‐nitrogen double bonds of the 5 H ‐[2,3]benzodiazepine ring system was also noticed.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom