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Synthesis and antimicrobial activity of some new N ‐(substituted phenyl)‐ N ′‐[2,3‐dihydro‐2‐oxido‐3‐(4′‐fluorophenyl)‐1 H ‐(1,3,2)benzoxazaphosphorin 2‐yl]ureas
Author(s) -
Haranath P.,
Kumar V. Sreedhar,
Reddy C. Suresh,
Raju C. Naga,
Reddy C. Devendranath
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440214
Subject(s) - chemistry , antimicrobial , triethylamine , toluene , medicinal chemistry , organic chemistry , stereochemistry
ubstituted benzoxazaphosphorin 2‐yl ureas were synthesized by reacting 2‐(4‐fluoro‐phenylamino)‐methylphenol (4) with different carbamidophosphoric acid dichlorides (3) in the presence of triethylamine in dry toluene at 45‐50 °C and characterized by spectral data. These compounds were found to possess good antimicrobial activity.