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A new site‐selective route for synthesis of functionalized imidazo[2,1‐ c ][1,2,4]triazoles
Author(s) -
Shawali Ahmad S.,
Abdallah Magda A.,
Mosselhi Mosselhi A. N.,
Elewa Mahmoud S.
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440202
Subject(s) - chemistry , halide , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry
Reactions of 4‐arylhydrazono‐2‐methylthio‐imidazolin‐5(1 H )‐one 3 with various hydrazonoyl halides 1 proved to be site‐selective and yielded the respective imidazo[2,1‐ c ][1,2,4]triazole derivatives 8 . The structure of the latter was elucidated by X‐ray analysis and the mechanism of the studied reactions was discussed.