Premium
New routes to steroidal heterocyclic derivatives: Synthesis of biologically active pyrazolyl‐ and isoxazolylpregnene derivatives
Author(s) -
Abdelhamid Abdou O.,
Abdelhalim Mervat M.,
Elmegeed Gamal A.
Publication year - 2007
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570440102
Subject(s) - chemistry , biological activity , derivative (finance) , chemical transformation , combinatorial chemistry , transformation (genetics) , organic chemistry , elemental analysis , spectral analysis , in vitro , biochemistry , spectroscopy , physics , quantum mechanics , economics , financial economics , gene
Pyrazolyl‐ and isoxazolylpregnene derivatives were synthesized from the appropriate hydrazonoyl chlorides and hydroximoyl chlorides with enaminoprogesterone derivative. The newly synthesized compounds were elucidated by elemental analysis, spectral data and chemical transformation. Some products were tested towards some bacteria and some Fungal‐plant pathogens