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An efficient approach towards three component coupling of one pot reaction for synthesis of functionalized benzopyrans
Author(s) -
Kumar B. Sunil,
Srinivasulu N.,
Udupi R. H.,
Rajitha B.,
Reddy Y. Thirupathi,
Reddy P. Narsimha,
Kumar P. S.
Publication year - 2006
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570430641
Subject(s) - chemistry , component (thermodynamics) , benzopyrans , coupling reaction , simplicity , benzopyran , combinatorial chemistry , coupling (piping) , catalysis , solvent , one pot synthesis , scale (ratio) , reaction conditions , organic chemistry , thermodynamics , mechanical engineering , philosophy , physics , epistemology , quantum mechanics , engineering
Three component coupling of one pot reaction which servers as the most convenient route to the synthesis of benzopyran derivatives using the TiCl 4 catalyst (10 mol %) under solvent free conditions is described. The procedure offers a systematic method with a number of advantages including operational simplicity, neat reactions, reduced reaction time, high yields of products and applicability to large scale reactions.