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Synthesis of 2‐aryl and coumarin substituted benzothiazole derivatives
Author(s) -
Kenny Rajesh S.,
Mashelkar Uday C.
Publication year - 2006
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570430535
Subject(s) - chemistry , benzothiazole , coumarin , aryl , combinatorial chemistry , organic chemistry , medicinal chemistry , alkyl
A facile and effective method for the synthesis of some benzothiazole derivatives is described. The method involves the action of aryl aldehyde and o ‐aminothiophenol in acetic acid resulting into in situ formation of the thiol substituted Schiff's base and its cyclization to 2‐aryl benzothiazole upon prolonged heating.