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The reaction of aryl and heteroarylhydrazines with aryl‐trifluoromethyl β‐diketones
Author(s) -
Singh Shiv P.,
Kumar Vinod,
Aggarwal Ranjana,
Elguero Jose
Publication year - 2006
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570430428
Subject(s) - chemistry , trifluoromethyl , aryl , medicinal chemistry , organic chemistry , stereochemistry , alkyl
We report the results obtained when five aromatic or heteroaromatic hydrazines react with six β‐diketones bearing trifluoromethyl and aryl substituents. Forty‐two compounds have been isolated corresponding to two isomeric trifluoromethyl pyrazoles and the intermediate 5‐CF 3 , 5‐OH pyrazolines. The results have provided useful information for establishing the mechanism of the synthesis of pyrazoles.