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Synthesis of oxadiazoloquinoxaline, oxathiadiazoloquinoxaline and oxadiazolobenzothiazine derivatives
Author(s) -
Fylaktakidou Konstantina C.,
Litinas Konstantinos E.,
Saragliadis Athanasios,
Adamopoulos Spyros G.,
Nicolaides Demetrios N.
Publication year - 2006
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570430309
Subject(s) - chemistry , phosgene , ethyl chloroformate , derivative (finance) , chloroformate , organic chemistry , medicinal chemistry , economics , financial economics
Bis‐amidoxime 1 reacts with phosgene, thiophosgene and thionylchloride to give the corresponding bisfused oxadiazolo‐ and oxathiadiazoloquinoxalines 2, 4, 5 along with the unexpected furazano‐derivative 3 , while monoamidoximes 9, 13 by treatment with ethyl chloroformate affords the oxadiazoloquinoxaline and the oxadiazolobenzothiazine derivatives 14, 15 along with the dicarboxylated product 16 .

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