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Iodobenzene diacetate on alumina: Efficient synthesis of 1,3,4‐oxadiazolyl‐1,8‐naphthyridines in solventless system using microwaves
Author(s) -
Mogilaiah K.,
Uma Rani J.,
Sakram B.,
Vasudeva Reddy N.
Publication year - 2006
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570430235
Subject(s) - chemistry , iodobenzene , microwave irradiation , acetic acid , microwave , aryl , solvent , microwave heating , organic chemistry , combinatorial chemistry , catalysis , physics , alkyl , quantum mechanics
Abstract1‐(5‐Aryl‐[1,3,4]oxadiazol‐2‐ylmethyl)‐3‐( p ‐methoxyphenyl)‐1 H ‐[1,8]naphthyridin‐2‐ones ( 5 ) were synthesized by the oxidative cyclization of [2‐oxo‐3‐( p ‐methoxyphenyl)‐2 H ‐[1,8]naphthyridin‐1‐yl]acetic acid arylidene‐hydrazides ( 4 ) with alumina‐supported iodobenzene diacetate (IBD) in solvent‐free conditions under microwave irradiation. The products are obtained in good yields and in a state of high purity.