The synthesis of 4‐acylamino‐1,2,4‐triazole derivatives in the reaction of α‐hydroxyacid hydrazidesand orthoesters | Zendy

Zieliński W. | Zendy; Kudelkoand A. | Zendy; Czardybon W. | Zendy

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The synthesis of 4‐acylamino‐1,2,4‐triazole derivatives in the reaction of α‐hydroxyacid hydrazidesand orthoesters

Author(s) -

Zieliński W.,

Kudelkoand A.,

Czardybon W.

Publication year - 2005

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570420720

Subject(s) - chemistry , acetic acid , derivative (finance) , combinatorial chemistry , organic chemistry , economics , financial economics

There action of α‐hydroxyacid hydrazides and orthoesters in ethano1‐acetic acid solution has been studied and aseries of 4‐acylamino‐1,2,4‐triazoles has been obtained as the final products. Some acyclic intermediates: 1‐acyl‐2‐ethoxymethylenehydrazines and N,N′ –bis(methanecarbonylamino) formamidine derivative have been also separated during the process. The structures of products was confirmed by typical spectro‐scopicmethods and X‐ray analysis.

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