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Stereoselective synthesis of new dihydropyrimidinone glycoconjugates #
Author(s) -
Sharma G. V. M.,
Reddy K. Laxmi,
Lakshmi P. Sree,
Krishna Palakodety Radha
Publication year - 2005
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570420719
Subject(s) - chemistry , glycoconjugate , stereoselectivity , sugar , biginelli reaction , solvent , organic chemistry , nuclear chemistry , catalysis , biochemistry
Stereoselective synthesis of dihydropyrimidinone glycoconjugates in high yields, from different sugar aldehydes, by a three‐component coupling (Biginelli) reaction is reported. In this new method, HC1 generated ‘in situ’ from2,4,6‐trichloro[l,3,5]triazine(TCT; 10 mol%), was used under mild and solvent free reaction conditions.