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Synthesis of 2‐(3‐indolyl)‐1,4‐naphthoquinones using 3‐iodoindoles
Author(s) -
Tanoue Yasuhiro,
Hamada Moritsugu,
Kai Norihisa,
Sakata Kazunori,
Hashimoto Mamoru,
Nagai Takeshi
Publication year - 2005
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570420625
Subject(s) - chemistry , indole test , naphthoquinone , combinatorial chemistry , stereochemistry , organic chemistry , medicinal chemistry
The usefulness of 3‐iodoindoles available for introduction of an indole unit is presented. The reaction of various halo‐3‐iodoindoles with 1,4‐naphthoquinone gave the corresponding 2‐(3‐indolyl)‐1‐4,naphthoquinones in moderate yields. The 3‐iodoindole was used for synthesis of a compound containing both naph‐thazarin and indole skeletons.