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One‐pot synthesis of novel N ‐cyclopropyldecahydroacridine‐1,8‐dione derivatives under microwave irradiation
Author(s) -
Tu Shujiang,
Zhang Xiaojing,
Shi Feng,
Li Tuanjie,
Wang Qian,
Zhu Xiaotong,
Zhang Jinpeng,
Xu Jianing
Publication year - 2005
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570420618
Subject(s) - dimedone , chemistry , microwave irradiation , aldehyde , microwave , organic chemistry , nuclear chemistry , irradiation , medicinal chemistry , catalysis , physics , quantum mechanics , nuclear physics
A series of new N ‐cyclopropyldecahydroacridine‐1,8‐dione derivatives were synthesized by one‐pot reaction of aromatic aldehyde, dimedone (or 1,3‐cyclohexanedione) and cyclopropanamine in solution of glycol and water under microwave irradiation with excellent yields (78‐94%) and short reaction time (5‐10 min).