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Synthesis of a new enantiopure chiral aza crown ether and its application in enantiomeric separation
Author(s) -
Wang ChengYun,
Wang DaHui,
Leng TaoHua,
Yu QingSen
Publication year - 2005
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570420602
Subject(s) - enantiopure drug , chemistry , enantiomer , crown ether , ether , organic chemistry , stereochemistry , enantioselective synthesis , catalysis , ion
A new enantiopure chiral aza crown ether ( S,S )‐1,7‐bis(4‐phenyl‐5‐hydroxy‐2‐oxo‐3‐ zapentyl)‐1,7‐diaza‐12‐crown‐4 ligand (1) has been synthesized and used as a chiral selector in the enantiomeric separation of D/L‐carnitine by capillary electrophoresis.