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An efficient one‐pot synthesis of novel pyrimidoquinoline derivatives under microwave irradiation without catalyst
Author(s) -
Tu Shujiang,
Fang Fang,
Li Tuanjie,
Zhu Songlei,
Zhang Xiaojing
Publication year - 2005
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570420436
Subject(s) - chemistry , catalysis , aldehyde , microwave irradiation , yield (engineering) , condensation , condensation reaction , microwave , environmentally friendly , organic chemistry , combinatorial chemistry , nuclear chemistry , ecology , materials science , biology , metallurgy , thermodynamics , physics , quantum mechanics
A series of pyrimidoquinoline derivatives were synthesized through one‐pot condensation of 2,6‐diaminopyrimidin‐4‐one, aldehyde and cyclic a 1,3‐dicarbonyl compound in glycol under microwave irradiation without catalyst. The protocol in the absence of catalyst has the advantage of good yield (87‐95%), short reaction time (4‐7 min) and an environmentally friendly technique.