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A new entry to pyrazolo[4,3‐ e ][1,4]diazepines. Facile synthesis of pyrazolo [4,3‐ e ][1,4]diazepin‐5,8‐diones, 5,6,8‐triones and pyrazolo[4,3‐ e ]pyrrolo‐[1,2‐ a ][1,4]diazepin‐5,10‐diones
Author(s) -
Reddy Nalla Ram,
Reddy Ghanta Mahesh,
Reddy Padi Pratap
Publication year - 2005
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570420429
Subject(s) - chemistry , diazepine , ring (chemistry) , combinatorial chemistry , pyrazole , stereochemistry , medicinal chemistry , organic chemistry
A facile approach to pyrazolo[4,3‐ e ][1,4]diazepin‐5,8‐diones and pyrazolo[4,3‐ e ]pyrrolo[1,2‐ a ][1,4]‐diazepin‐5,10‐diones is reported. Strategy involved the utility of α‐amino acid as a three‐atom segment in the construction of diazepine skeleton on the preformed pyrazole ring.