Premium
A synthesis of potential new antiarrhythmic agents
Author(s) -
Javed Tariq,
Shattat Ghassan F.
Publication year - 2005
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570420206
Subject(s) - chemistry , indole test , potassium carbonate , aryl , potassium , organic chemistry , ethyl ester , combinatorial chemistry , alkyl
N ‐Ethylation of substituted ethyl 1 H ‐indole‐2‐carboxylates with iodoethane and potassium carbonate gave substituted ethyl 1‐ethyl‐1 H ‐indole‐2‐carboxylates. The later compounds on treatment with a range of aryl amines with varying structural complexity, gave the desired ethyl 1 H ‐indole‐2‐carboxamide analogues.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom