Synthesis of some pyrazole‐3‐carboxylic acid‐hydrazide and pyrazolopyridazine compounds | Zendy

İlhan İ Özer | Zendy; Saripinar Emin | Zendy; Akçamur Yunus | Zendy

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Synthesis of some pyrazole‐3‐carboxylic acid‐hydrazide and pyrazolopyridazine compounds

Author(s) -

İlhan İ Özer,

Saripinar Emin,

Akçamur Yunus

Publication year - 2005

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570420117

Subject(s) - chemistry , phenylhydrazine , hydrazide , pyrazole , yield (engineering) , furan , carboxylic acid , carbon 13 nmr , elemental analysis , organic chemistry , pyrazolone , medicinal chemistry , metallurgy , materials science

Furan‐2,3‐diones 1a‐c react with various hydrazines 2a‐c under different conditions to yield the pyrazole‐3‐carboxylic acid‐hydrazide 3a‐d . Cyclocondensation reactions of 1a or 7 with phenylhydrazine lead to derivatives of pyrazolo[3,4‐ d ]pyridazinones 6 and 8 , respectively. The structures of all products were confirmed by elemental analysis, IR, 1 H‐ and 13 C‐NMR spectroscopic measurements.

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