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Microwave‐assisted synthesis of phenylenedi(4′,4“‐tetrahydroquinoline) and di(4′,4”‐tetrahydropyridine) derivatives
Author(s) -
Tu Shujiang,
Fang Fang,
Zhu Songlei,
Li Tuanjie,
Zhang Xiaojing,
Zhuang Qiya,
Ji Shuijun,
Zhang Yong
Publication year - 2005
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570420105
Subject(s) - chemistry , bifunctional , pyridine , microwave irradiation , yield (engineering) , bicyclic molecule , phthalide , organic chemistry , isophthalic acid , combinatorial chemistry , terephthalic acid , polyester , catalysis , materials science , metallurgy
Abstract The synthesis of bifunctional pyridine and quinolione derivatives were investigated using terephthalic and isophthalic aldehydes as a precursor. The reaction proceeds under microwave irradiation with good yield (70–92%) and short reaction time (7–9 min.). We provide a rapid and efficient method of synthesizing a range of bifunctional monocyclic and bicyclic products related to 1,4‐dihydropyridines (1,4‐DHPs).