The preparation of benzoisothiazolo[1,2‐ b ][1,2]isoquinolin‐11‐one‐1,1‐dioxides from dilithiated  ortho ‐toluic acids and lithiated methyl 2‐(aminosulfonyl)benzoate | Zendy

Dunn S. Patrick | Zendy; Walters Matthew J. | Zendy; Metz Clyde R. | Zendy; Beam Charles F. | Zendy; Pennington William T. | Zendy; Krawiec Mariusz | Zendy

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The preparation of benzoisothiazolo[1,2‐ b ][1,2]isoquinolin‐11‐one‐1,1‐dioxides from dilithiated ortho ‐toluic acids and lithiated methyl 2‐(aminosulfonyl)benzoate

Author(s) -

Dunn S. Patrick,

Walters Matthew J.,

Metz Clyde R.,

Beam Charles F.,

Pennington William T.,

Krawiec Mariusz

Publication year - 2004

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570410626

Subject(s) - lithium diisopropylamide , chemistry , ring (chemistry) , medicinal chemistry , lithium (medication) , organic chemistry , deprotonation , ion , medicine

Select dilithiated ortho ‐toluic acids were prepared in excess lithium diisopropylamide and condensed with methyl 2‐(aminosulfonyl)benzoate followed by a twofold cyclization of intermediates to afford benzoisothiazolo[1,2‐ b ][1,2]isoquinolin‐11‐one‐1,1‐dioxides, a new fused‐ring heterocyclic system.

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