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Synthesis and antimicrobial activity of N ‐(substituted)‐ N ‐[1,2,4,8,10,11‐hexachloro‐6‐oxido‐12 H ‐dibenzo( d,g )(1,3,2)‐dioxaphosphocin‐6‐yl]ureas
Author(s) -
Haranath P.,
Anasuyamma U.,
Reddy P. Vasu Govardhana,
Reddy C. Sureshx
Publication year - 2004
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570410625
Subject(s) - chemistry , triethylamine , antimicrobial , toluene , medicinal chemistry , organic chemistry
Abstract Substituted dibenzo dioxaphosphocin‐6‐yl ureas were synthesized by reacting hexachlorophene (4) with different carbamidophosphoric acid dichlorides (3) in the presence of triethylamine in dry toluene at 45‐50 o C. Their IR, 1 H, 13 C and 31 P NMR spectral data is discussed. These compounds were found to possess good antimicrobial activity.