Premium
A novel synthesis of 1‐substituted 2 H ‐isoquinolin‐3‐ones
Author(s) -
Cánepa Alicia S.,
Bravo Rodolfo D.
Publication year - 2004
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570410620
Subject(s) - chemistry , intramolecular force , combinatorial chemistry , medicinal chemistry , stereochemistry
The intramolecular cyclization of 2‐acylphenylacetonitriles 1 under strongly acidic conditions easily affords 1‐substituted 2 H ‐isoquinolin‐3‐ones 2 in excellent yields.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom