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New results on the reactivity of 5,6‐diamino‐4‐hydroxy‐2‐mercaptopyrimidine
Author(s) -
Cosimelli Barbara,
Iadanza Manuela,
Novellino Ettore,
Spisani Raffaella
Publication year - 2004
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570410606
Subject(s) - chemistry , reactivity (psychology) , alkyl , stereochemistry , medicinal chemistry , organic chemistry , medicine , alternative medicine , pathology
The reaction of 5,6‐diamino‐4‐hydroxy‐2‐mercaptopyrimidine with mono‐ and α,ω‐dihalocompounds has been reinvestigated. Alkyl derivatives of 5‐amino group, not previously described, have been obtained as reaction products. A comparison with the reactivity of 6‐amino‐4‐hydroxy‐2‐mercaptopyrimidine has been also performed.