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Synthesis of new isoxazoles derivatives attached to sugar moieties
Author(s) -
Pinheiro Jorge M.,
Ismael M. Isabel,
Figueiredo J. Albertino,
Silva Artur M. S.
Publication year - 2004
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570410605
Subject(s) - chemistry , iodine , sugar , intramolecular force , aldehyde , organic chemistry , iodide , potassium carbonate , sodium iodide , sodium carbonate , sodium , catalysis
This work reports the synthesis of isoxazoles linked to sugar derivatives in different positions of furanosidic rings, by intramolecular oxidative cyclization of α,β‐unsaturated oximes with iodine, potassium iodide and sodium hydrogen carbonate. These oximes were obtained from aldehyde‐sugar derivatives.