Ring closure reactions of 3‐arylhydrazonoalkyl‐quinolin‐2‐ones to 1‐aryl‐pyrazolo[4,3‐ c ]quinolin‐2‐ones | Zendy

Stadlbauers Wolfgang | Zendy; Hojas Gerhard | Zendy

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Ring closure reactions of 3‐arylhydrazonoalkyl‐quinolin‐2‐ones to 1‐aryl‐pyrazolo[4,3‐ c ]quinolin‐2‐ones

Author(s) -

Stadlbauers Wolfgang,

Hojas Gerhard

Publication year - 2004

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570410505

Subject(s) - chemistry , quinoline , aryl , ring (chemistry) , closure (psychology) , differential scanning calorimetry , medicinal chemistry , combinatorial chemistry , stereochemistry , organic chemistry , thermodynamics , alkyl , physics , economics , market economy

4‐Hydroxy‐3‐arylhydrazonoalkyl‐2‐quinolones 6 or reactive derivatives such as 3‐arylhydrazonoalkyl‐4‐tosyloxy‐2‐quinolones 7 or 4‐chloro‐3‐arylhydrazonoalkyl‐2‐quinolones 14 , which are obtained via 3‐acyl‐4‐hydroxyquinolones 4, 10 or 3‐phenylarrmomethylene‐quinoline‐2,4‐diones 12 , cyclize in excellent yields to 1‐aryl‐pyrazolo[4,3‐ c ]quinolin‐4‐ones (11). The cyclization conditions were investigated by differential scanning calorimetry (DSC).

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