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Indium‐mediated facile preparation of 2‐(heterocyclic thio)‐1‐(2,3,4‐trimethoxyphenyl)ethanone in aqueous media
Author(s) -
Yang Song,
Song BaoAn,
Zhang Hua,
Hu DeYu,
Jin LinHong,
Liu Gang
Publication year - 2004
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570410423
Subject(s) - chemistry , thio , aqueous medium , indium , antifungal , organic chemistry , aqueous solution , combinatorial chemistry , medicine , dermatology
An environmentally benign and efficient process for the preparation of 1‐(2,3,4‐trimethoxyphenyl)‐2‐substituted heterocyclic thio ethanone derivatives was achieved by the reactions of mercapto compounds with 2‐bromo‐1‐(2,3,4‐trimethoxyphenyl)ethanone in water mediated by indium in very high yields. Antifungal activities of the compounds were examined and moderate activity was obtained.