Synthesis and characterization of new biologically active 2‐(1,3‐disubstituted pyrazolyl)chromones and corresponding pyrimidine, thiopyrimidine, pyrazolyl derivatives | Zendy

Joshia N. S. | Zendy; Karale B. K. | Zendy; Gill C. H. | Zendy; Bhirud S. B. | Zendy

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Synthesis and characterization of new biologically active 2‐(1,3‐disubstituted pyrazolyl)chromones and corresponding pyrimidine, thiopyrimidine, pyrazolyl derivatives

Author(s) -

Joshia N. S.,

Karale B. K.,

Gill C. H.,

Bhirud S. B.

Publication year - 2004

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570410410

Subject(s) - chemistry , pyrimidine , phosphodiesterase , combinatorial chemistry , biological activity , organic chemistry , stereochemistry , in vitro , biochemistry , enzyme

A series of 2‐(1‐methyl‐3‐ n ‐propylpyrazol‐5‐yl)‐chromones with interesting Phosphodiesterase IV inhibitition activities were synthesized. Different derivatives of the titled compounds like aminopyrimidine, thiopyrimidine, pyrazolyl were synthesized and their Phosphodiesterase IV inhibitition activities were checked.

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