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New one step synthesis of crown compounds containing a 1,3,4‐thiadiazole moiety
Author(s) -
Bentiss Fouad,
Lebrini Mounim,
Lagrenée Michel
Publication year - 2004
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570410319
Subject(s) - chemistry , moiety , nucleophilic substitution , anhydrous , polymer chemistry , nucleophile , nuclear magnetic resonance spectroscopy , polyethylene glycol , base (topology) , ethylene glycol , potassium carbonate , organic chemistry , mathematical analysis , mathematics , catalysis
New macrocyclic polyether compounds containing a 2,5‐bis(2‐hydroxyphenyl)‐1,3,4‐thiadiazole moiety have been prepared by a nucleophilic substitution reaction involving ethylene or polyethylene glycol ditosylate and a bisphenol, the 2,5‐bis(2‐hydroxyphenyl)‐1,3,4‐thiadiazole, with solid anhydrous carbonate as a base. The structures of the macrocycles obtained were firmly established by 1 H and 13 C nmr spectroscopy and their mass spectra.