Premium
Consecutive isomerization and cyclization of 3‐(2‐aminophenyl)‐1‐arylprop‐2‐yn‐1‐ols leading to 2‐arylquinolines in the presence of potassium hydroxide
Author(s) -
Cho Chan Sik,
Lee Na Young,
Kim TaeJeong,
Shim Sang Chul
Publication year - 2004
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570410317
Subject(s) - chemistry , isomerization , potassium hydroxide , medicinal chemistry , potassium , hydroxide , organic chemistry , catalysis
3‐(2‐Aminophenyl)‐1‐arylprop‐2‐yn‐1‐ols are readily converted to 2‐arylquinolines in good yields in ethanol at 80° in the presence of potassium hydroxide via domino isomerization and cyclization.