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One‐pot synthesis of the indole derivative 4‐chloro‐3‐sulphamoyl‐ N ‐(2,3‐dihydro‐2‐methyl‐1 H ‐indol‐1‐yl)benzamide (indapamide)
Author(s) -
Ziobro Barbara,
Sienkiewicz Barbara,
Kowalski Piotr
Publication year - 2004
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570410115
Subject(s) - chemistry , indapamide , benzamide , indole test , derivative (finance) , stereochemistry , medicinal chemistry , combinatorial chemistry , pharmacology , medicine , diuretic , financial economics , economics
New methods for the synthesis the indole derivative, Indapamide (1), using mixed anhydrides of the general formula R1COOCOOR2 (2) or DCC (N,N'‐dicyclohexylcarbodiimide) (3), are described.