Simple and efficient cleavage reaction of the boc group in heterocyclic compounds | Zendy

Nadia Klai | Zendy; Malika Berredjem | Zendy; Nawel Khettache | Zendy; Yazid Belghit Med | Zendy; Zine Régaïnia | Zendy; Aouf NourEddine | Zendy

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Simple and efficient cleavage reaction of the boc group in heterocyclic compounds

Author(s) -

Nadia Klai,

Malika Berredjem,

Nawel Khettache,

Yazid Belghit Med,

Zine Régaïnia,

Aouf NourEddine

Publication year - 2004

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570410109

Subject(s) - chemistry , regioselectivity , yield (engineering) , isocyanate , cleavage (geology) , group (periodic table) , organic chemistry , medicinal chemistry , stereochemistry , combinatorial chemistry , catalysis , materials science , geotechnical engineering , fracture (geology) , engineering , metallurgy , polyurethane

Dedicated to the memory of Pr. Ladjama Daif A series of chiral cyclosulfamides have been synthesized by alkaline cyclisation starting from N‐benzoylamino acids (Ala, Val, Leu, Phe) derivatives and chlorosulfonyl isocyanate. A simplified and regioselective deprotection of the cyclic compounds ( cyclosulfamides ) containing the tert ‐butyloxycarbonyl group (Boc) has been achieved in good yield by fusion under reduced pressure.

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