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A novel synthetic approach for the synthesis of pyridocarbazole alkaloids
Author(s) -
Ergün Yavuz,
Okaya Gürol,
Patir Süleyman
Publication year - 2003
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570400608
Subject(s) - chemistry , carbazole , stereochemistry , combinatorial chemistry , alkaloid , organic chemistry
The synthesis of 11‐methyl‐6 H ‐pyrido[4,3‐ b ]carbazole‐1(2 H )‐one (5), which can be important for the synthesis of other pyridocarbazole alkaloids and especially 1‐substituted ellipticines, is described. Construction of the tetracyclic structure was achieved by a new route and two important precursor compounds (4a and 4b) for the synthesis of pyridocarbazole alkaloids and also many new tetrahydrocar‐bazole derivatives (7, 8, 9, 10, 11, 12, 13) were synthesized.