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A convenient preparation of 3‐acetyl‐5‐methylisoxazole
Author(s) -
Sauers Ronald R.,
Van Arnum Susan D.
Publication year - 2003
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570400415
Subject(s) - chemistry , ketone , methyl vinyl ketone , organic chemistry , methyl ketone , catalysis
Starting from 2,5‐hexanedione ( 4 ), a one‐pot preparation of 3‐acetyl‐5‐methylisoxazole ( 1 ) is described. 3‐Acetyl‐5‐methylisoxazole ( 1 ) is a useful compound for the preparation of 3‐oxobutyronitrile ( 10 ) and for 3‐vinyl‐(5‐methyl isoxazolyl) ketone ( 2 ).