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Synthesis of novel benzo[ h ] [1,6]naphthyridines via a rearrangement of hexahydro‐5 H ‐pyrrolo [2,1 ‐ c ] [1,4]benzodiazepines
Author(s) -
Hinschberger Antoine,
Fabis Frédéric,
Santos Jana SopkovaDe Oliveira,
Rault Sylvain
Publication year - 2003
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570400209
Subject(s) - chemistry , stereochemistry , medicinal chemistry
Heating of hexahydro‐5 H ‐pyrrolo[2,1‐ c ][1,4]benzodiazepine‐2,5,11‐trione in boiling phosphoryl chloride led to a rearranged product like 3,5‐dichlorobenzo[ h ][1,6]naphthyridine. This structure was established from X‐ray diffraction analysis.
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