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The synthesis of 4‐amino‐3‐(2‐pyridyl)pyrazolo[5,1‐ c ][1,2,4]triazine and some of its derivatives
Author(s) -
Cankař Petr,
Slouka Jan
Publication year - 2003
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570400109
Subject(s) - chemistry , triazine , pyrazole , azo coupling , chloride , medicinal chemistry , diazonium compounds , organic chemistry
A mixture of both geometrical isomers of hydrazones 3a‐3e was obtained by the coupling reactions of pyrazole‐3‐diazonium salts 2a‐2d and benzenediazonium chloride 2e with 2‐pyridylacetonitrile 1 . Hydrazones 3a‐3d were cyclized to the corresponding 4‐amino‐3‐(2‐pyridyl)pyrazolo[5,1‐ c ][1,2,4]triazines 4a‐4d.
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