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Carbocyclic galanthamin analogs: 4a,5,9,10,11,12‐hexahydro‐6 H ‐benzo[ b ]cyclohepta[ cd ]benzofurans
Author(s) -
Treu Matthias,
Hametner Christian,
Frohlich Johannes,
Jordis Ulrich,
Mereiter Kurt
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390626
Subject(s) - chemistry , stereochemistry , tandem , medicinal chemistry , composite material , materials science
The synthesis of a novel unnatural carbocyclic analog of the acetylcholine esterase inhibitor galanthamine with a K 3 [Fe(CN) 6 ] promoted oxidative tandem cyclization as the key step is reported.